Rabbi Samlai explains that six hundred and thirteen commandments were communicated to Moses; three hundred and sixty-five negative, according to the number of days in the year, and two hundred and forty-eight positive, according to the number of members in the human body. Rav Hamnunah asked what was the Scripture proof for this. The reply was (Deut. xxxiii. 4), " Moses commanded us a law" (Torah), which by Gematria answers to six hundred and eleven. " I am,8 and "Thou shalt have no other," which we heard from the Almighty Himself, together make up six hundred and thirteen.
Why 613 Commandments Matches the Human Body
Makkot 23b (Hebraic Literature, 1901)