Seeing that neither the loss of all he had nor the death of his children could change his pious heart, Satan appeared before God a second time, and requested that Job himself, his very person, be put into his hand. God granted Satan's plea, but he limited his power to Job's body, his soul he could not touch. In a sense Satan was worse off than Job. He was in the position of the slave that has been ordered by his master to break the pitcher and not spill the wine.
Satan now caused a terrific storm to burst over the house of Job. He was cast from his throne by the reverberations, and he lay upon the floor for three hours. Then Satan smote his body with leprosy from the sole of his foot unto his crown. This plague forced Job to leave the city, and sit down outside upon an ash-heap, for his lower limbs were covered with oozing boils, and the issue flowed out upon the ashes. The upper part of his body was encrusted with dry boils, and to ease the itching they caused him, he used his nails, until they dropped off together with his fingertips, and he took him a potsherd to scrape himself withal. His body swarmed with vermin, but if one of the little creatures attempted to crawl away from him, he forced it back, saying, "Remain on the place whither thou wast sent, until God assigns another unto thee." His wife, fearful that he would not bear his horrible suffering with steadfastness, advised him to pray to God for death, that he might be sure of going hence an upright man. But he rejected her counsel, saying, "If in the days of good fortune, which usually tempts men to deny God, I stood firm, and did not rebel against Him, surely I shall be able to remain steadfast under misfortune, which compels men to be obedient to God." And Job stuck to his resolve in spite of all suffering, while his wife was not strong enough to bear her fate with resignation to the will of God.