Rabbi Simeon said: From Seth arose and were descended all the generations of the righteous. From Cain arose and were descended all the generations of the wicked, who rebel and sin, who rebelled against their Rock, and they said: We do not need the drops of Thy rain, neither to walk in Thy ways, as it is said, "Yet they said unto God, Depart from us" (Job 21:14).
Rabbi Meir said: || The generations of Cain went about stark naked, men and women, just like the beasts, and they defiled themselves with all kinds of immorality, a man with his mother or his daughter, or the wife of his brother, or the wife of his neighbour, in public and in the streets, with evil inclination which is in the thought of their heart, as it is said, "And the Lord saw that the wickedness of man was great in the earth" (Gen. 6:5).