What is meant by the tree of the knowledge of good and evil? (Genesis 2:9)

This indeed exhibits that meaning which is sought for in the letter of the Scriptures more clearly to the sight, as it bears a manifest allegory on the face of it. What is meant then under this figure is prudence, which is the comprehension of science, by which all things are known and distinguished from one another, whether they be good and beautiful, or bad and unseemly, or in short every sort of contrariety is discerned; since some things belong to the better class, and some to the worse. Therefore the wisdom which exists in this world is not in truth God himself, but the work of God; that it is which sees and thoroughly investigates every thing. But the wisdom which exists in man sees in an incorrect and mixed manner with somewhat darkened eyes; for it is found to be incompetent to see and comprehend clearly and without alloy each particular thing separately. Moreover, there is a kind of deception mingled with human wisdom; since very often there are some shadows found which hinder the eyes from contemplating a brilliant light; since what the eye is in the body, such also is the mind and wisdom in the soul.