The circumstances connected with the birth of her twin sons were as remarkable as those during the period of Rebekah's pregnancy. Esau was the first to see the light, and with him all impurity came from the womb; Jacob was born clean and sweet of body. Esau was brought forth with hair, beard, and teeth, both front and back, and he was blood-red, a sign of his future sanguinary nature. On account of his ruddy appearance he remained uncircumcised.

Isaac, his father, feared that it was due to poor circulation of the blood, and he hesitated to perform the circumcision. He decided to wait until Esau should attain his thirteenth year, the age at which Ishmael had received the sign of the covenant. But when Esau grew up, he refused to give heed to his father's wish, and so he was left uncircumcised. The opposite of his brother in this as in all respects, Jacob was born with the sign of the covenant upon his body, a rare distinction.

But Esau also bore a mark upon him at birth, the figure of a serpent, the symbol of all that is wicked and hated of God.