"As smoke is driven away, so You drive them away; as wax melts before fire, the wicked shall perish before God. David said before the Almighty that the wicked are nothing but smoke. They are like smoke that is driven away, not like smoke that has substance. Another interpretation of 'as smoke is driven away' refers to the wicked.
It is like a parable of a king who had servants in his palace. The king was in the upper palace while his servants in the lower palace kindled the fire and smoked it so that the smoke would rise up to him. Similarly, the wicked are like smoke from below. Isaiah says, "the people who provoke Me are as good as dead; their bodies will rot away, and they will become like ashes."
These are the wicked and they are nothing, as it says, "For the wicked will perish, and the enemies of the Lord will be like the glory of the pastures; they vanish—like smoke they vanish away." Therefore, "as smoke is driven away, so You drive them away." The wicked will be destroyed, and the righteous will rejoice, as it says, "The righteous shall rejoice and be glad before God; they shall also be merry and joyful."