Targum Pseudo-Jonathan on Genesis 10:9 gives us the first great villain after the Flood. He was a mighty rebel before the Lord; therefore it is said, From the day that the world was created there hath not been as Nimrod, mighty in hunting, and a rebel before the Lord.
The plain Hebrew calls Nimrod a "mighty hunter before the Lord." The Aramaic sharpens the phrase. Not before as in in the sight of — before as in against. Nimrod is a rebel, and his rebellion is set up face to face with heaven. He is not a man who happens to sin. He is a man whose very identity is opposition to God.
And the Targum doubles down: from the day that the world was created there hath not been as Nimrod. No rebel so complete has ever walked the earth. Not the generation of the Flood. Not Cain. Nimrod stands in a category of his own.
Jewish tradition will later build Nimrod into the great tyrant who throws Abraham into the fiery furnace for refusing to worship idols. The Targum's sharp phrasing plants the seed for that whole later story. Nimrod is the archetype of the man who uses his strength to hunt not just animals, but souls.
The takeaway the Maggid draws: strength without submission becomes rebellion. A hunter who will not bow his head eventually hunts the conscience of others. That is the real crime Torah warns against when it remembers Nimrod.